I'm not sure how anyone could know definitively that this character and storyline will or won't be picked up again -- especially since the guy who came up with the character is the one who'll be running the show in the next full series.
And while I agree that the Doctor has and will have many significant relationships in his full and varied life, we've never met his spouse before -- so that does certainly stand out as unique thus far, because we haven't in fact seen him married half a dozen times before. If we're left at the end of the episode knowing that someday the Doctor is going to take a step we haven't seen him take in 40-odd years of TV history, I dunno, pretty significant in my book, and hard not to keep in mind while watching other future relationships develop. "Sure, he seems to love him/her/it -- but that's not the one he marries!"
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And while I agree that the Doctor has and will have many significant relationships in his full and varied life, we've never met his spouse before -- so that does certainly stand out as unique thus far, because we haven't in fact seen him married half a dozen times before. If we're left at the end of the episode knowing that someday the Doctor is going to take a step we haven't seen him take in 40-odd years of TV history, I dunno, pretty significant in my book, and hard not to keep in mind while watching other future relationships develop. "Sure, he seems to love him/her/it -- but that's not the one he marries!"